Fluoxetine is one of the most popular and affordable antidepressants. Fluoxetine is an antidepressant in the class of selective serotonin reuptake inhibitors that acts by inhibiting neuronal uptake of serotonin, which when low levels can cause depression, panic syndrome, anxiety or obsessive-compulsive symptoms. Serotonin is one of the neurotransmitters.
Fluoxetine was discovered by Eli Lilly and Company in 1972 and began medical use in 1986. It is on the World Health Organization’s list of essential medicines. It is available as a generic drug.
Major indications for fluoxetine treatment include depression related or not related to anxiety, bulimia nervosa, obsessive-compulsive disorder (OCD), panic disorder, and premenstrual dysphoric disorder, including PMS, irritability, and mood swings. Depression is a serious medical illness that involves your body and thoughts. If you are one of the people who have depression, the feelings do not go away you should avoid or prevent them taking fluoxetine. Sadness, thoughts of suicide, loss of interest to life persist and interfere with your everyday life and make your life unhappy and difficult. There are a variety of causes which may lead to depression, including genetic, environmental, and psychological and biochemical factors. Buy fluoxetine to treat it, depression usually starts between 15 and 30 years old.
A 2012 meta-analysis with individual data on the use of fluoxetine for the treatment of depression found that statistically and clinically significant benefit was observed regardless of baseline severity of depression, and there was no significant effect of baseline severity on observed effectiveness.
A 2009 systematic review by the National Institute for Nursing and Clinical Excellence (NICE) (which reviewed Kirsch but not subsequent meta-analyses) concluded that there was strong evidence for the effectiveness of SSRIs in treating moderate to severe depression, and some evidence for their effectiveness in treating mild depression. Both the NICE and Fournier analyses concluded that there is stronger evidence for the effectiveness of antidepressants in treating chronic mild depression (dysthymia) than for recent mild depression.
The efficacy of fluoxetine in the treatment of obsessive-compulsive disorder (OCD) has been demonstrated in two multicenter randomized phase III clinical trials. The combined results of these trials showed that 47% of patients who completed treatment at the higher dose showed significant improvement after 13 weeks of treatment, compared with 11% in the placebo group.
Fluoxetine can sometimes be used with another antidepressant, olanzapine, to treat manic depression caused by bipolar disorder. This combination can also be used to treat depression if at least 2 other drugs have already been used and symptoms have not improved.
Fluoxetine is an oral drug that is used to treat depression and other disorders. This medication may be of various forms. They are capsules (Fluoxetine 10 mg, fluoxetine 20 mg, fluoxetine 40 mg, fluoxetine 60 mg); tablets (10 mg, 15 mg and 20 mg) and oral suspension 20 mg/ml is also available. Fluoxetine is usually a solid gelatin capsule #4, with a white body and a blue or green cap; the contents of the capsules are pellets of white or nearly white. For adults the dose is 20-80 mg of fluoxetine 20 mg per day, for children recommended dose is 10-20 mg daily. Fluoxetine is also used to treat obsessive-compulsive disorder and bulimia. Buy fluoxetine 20 mg; it is the best way out if you feel yourself depressed.
Fluoxetine should be taken orally before or after meals, always at the doctor’s prescribed time, preferably in the morning or evening, to avoid insomnia; however, if a dose is missed at the usual time, it should be taken as soon as one remembers it, but the missed dose should be skipped if it is close to the time of the next dose. Don’t take a double dose to make up for a forgotten dose.
The form of fluoxetine for adults varies depending on the medical indication and includes:
- Depression: the maximum recommended dose is 60 mg per day, which may be increased every 2-4 weeks;
- Bulimia nervosa: the dose is 60 mg orally once a day;
- Obsessive-compulsive disorder: the recommended initial dose is 20 mg per day, which may be increased after several weeks to a maximum dose of 60 mg per day;
- Panic disorder: the recommended dose is 10 mg orally once daily in the morning, which may be increased to 20 mg once daily after one week of treatment. The maximum dose should not exceed 60 mg per day, divided into two doses in the morning and evening;
- Premenstrual dysphoric disorder: the starting dose is 20 mg orally once daily, taken continuously, which may be divided into two doses in the morning and evening. Another form of use is a dose of 20 mg per day, starting 14 days before menstruation, stopping on the first day of menstruation, and repeating this form of use every month.
Fluoxetine may take up to 4 weeks of treatment to achieve the desired effect, so dose increases should only be made in accordance with medical evaluation and recommendations.
Fluoxetine should not be taken without recommendation and the advice of a physician. It’s suggested to take the medicine as the prescriptions of the doctor. The drug should be consumed with quantity of water and shouldn’t be little or chewed. If you are taking the form of the medication, ensure the medication is quantified in a measuring cup and not in a household cup or spoon. The form should be taken in accordance with the prescriptions of the doctor. Doctors administer around 20-80 mg of the medicine to adults and for children. It takes about four weeks for the drug. In case you’re feeling unwell after taking this medication or confront any negative effects, inform your physician immediately. Don’t discontinue the use of the drug.
Possible side effects
The most common side effects that may occur with fluoxetine treatment include insomnia, headache, dizziness, drowsiness, fatigue, visual impairment, tremors, feelings of anxiety or nervousness, abdominal pain, loss of appetite, nausea, vomiting, diarrhea, dry mouth, increased sweating, hot flashes, weight changes, reduced sexual desire or impotence.
It is recommended that you stop using the drug and immediately seek medical attention or go to the nearest hospital if you experience symptoms of fluoxetine allergy, such as difficulty breathing, throat scratch, swelling of the mouth, tongue, or face, hives, fever, burning sensation in the eyes, pain, blisters on the skin, or skin flaking. Read more about symptoms of an allergic reaction.
The physician should also be told if the person has mood or behavioral disorders, anxiety, panic attacks, difficulty sleeping or impulsivity, irritability, agitation, aggression, depression, or suicidal ideation.
Does fluoxetine cause weight loss?
Fluoxetine may promote weight loss because of its side effect of reducing appetite, which may be useful for weight loss in people who are obese or overweight. However, the exact mechanism of how fluoxetine promotes weight loss is not fully understood, so its use is not indicated for treating obesity.
There are many things to consider before taking this medication.
In addition to the conditions listed above, tell your doctor. If you become pregnant while taking this medicine, do not stop taking it and do not become pregnant. The medicine is not suitable during pregnancy and for breastfeeding mothers, as it can cause harm. The medication can get into the breast milk, so it is not recommended to take this medication.
Taking fluoxetine may cause drowsiness, nausea, headache, loss of appetite, anxiety, insomnia, decreased sexual desire or sexual ability, runny nose, and other side effects. Consult your doctor or any other health care professional. Do not take the medicine on your own volition alone, it can be harmful to your health, remember that. If you miss a dose, take the missed dose as soon as possible, but if it is not yet time for your next dose, skip the missed dose. Do not take a double dose to make up for a missed dose.
Fluoxetine should not be used in children, pregnant or lactating women, or people using monoamine oxidase inhibitor (MAOI) medications such as isocarboxazide, phenelzine, or tranylcypromine. You should wait at least 14 days after ending treatment with MAOIs before starting fluoxetine.
Fluoxetine may also interfere with the effects of the following medications:
- Anxiety medications such as alprazolam, diazepam, and chlordiazepoxide;
- Depression medications such as imipramine, desipramine, or lithium;
- Epilepsy medications such as phenytoin or carbamazepine;
- Medications for schizophrenia or psychosis, such as clozapine or haloperidol.
It is important to tell your doctor or pharmacist about any medications or natural products used, such as tryptophan or St. John’s wort supplements, to avoid increasing the effects of fluoxetine and causing side effects
Alcoholic beverages should also be avoided during fluoxetine treatment, as they can increase side effects, mainly drowsiness and dizziness.
Where to buy fluoxetine online?
According to the current United Kingdom dispensing regulations, a doctor’s prescription is required in order to obtain strong antidepressants from pharmacies.
And antidepressants are no exception. Therefore, in theory, you cannot buy fluoxetine without a prescription.
It is possible to buy without a prescription only drugs to treat mild depressive disorders and drugs on a herbal basis.
But in most cases it is difficult to classify them as real antidepressants. It would be more correct to refer them to the class of sedatives. But you can buy fluoxetine online from the UK.
Use during pregnancy and lactation
Contraindicated in pregnancy and during lactation.
Use in patients with liver dysfunction
Fluoxetine is metabolized in the liver and excreted by the kidneys and the gastrointestinal tract. In patients with significant hepatic impairment, lower doses of fluoxetine should be prescribed or every other day.
Use in patients with impaired renal function
Fluoxetine is metabolized in the liver and excreted by the kidneys and through the gastrointestinal tract. No difference in plasma concentrations of fluoxetine and norfluoxetine in healthy subjects with normal renal function and in patients with significant renal impairment (creatinine clearance of 10 ml/min) requiring hemodialysis was found when taking fluoxetine at a dose of 20 mg/day for two months.
Fluoxetine storage condition
Keep fluoxetine at room temperature and away from children, avoid also sunlight.